全身PBMT

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全身PBMT

全身PBMT

PBM(Photobiomodulation)是指特定波长区域的光源在线粒体中生成ATP过程的术语。

该术语从2016年末开始出现于美国国立保健院医学学术信息分类体系MeSH(Medical Subject Heading)中未来治疗手段的主要关键词。虽然低强度激光治疗(Low Level Laser Theapy)也被作为术语使用，但设备技术和医学标准被统一定义为PBM(Photobiomodulation)。

经临床验证的PBMT

目前,有关被称为Photobiomodulation的LLLT研究论文已出版了5000多篇， 这些论文中的优秀论文被登载在美国国立保健院国立医学图书馆(NCBI)网站上。

PBMT Human Clinical Trials

PBM has been researched for more than a decade on various different diseases and had been acknowledged for its effectiveness. The list below shows some of the studies outlined. This would be a great reference point for a new clinical trial as well.

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PBM Human Clinical Trial

Click on the categories to see the related studies

Below chart displays several cases on randomized clinical trials (total patients, 6,500)

Photobiomodulation : systematic reviews
Category Author Review Published Year N n Rating Results
periodontitis University of Hong Kong Ren M 2017 7 180 C /1 Photobiomodulation therapy (PBMT) had helped to reduce the pocket depth within 1-2 months.
Diabetic foot ulcer Tchanque ... S 2016 4 131 C PBMT accelerated the healing process
Hair loss Zarei S 2016 5 394 B / C PBMT was beneficial for recovering hair loss (androgen) in both genders
Healing tooth extract Ribeiro S 2016 11 555 C PBMT had reduced the pain
Delayed onset muscle syndrome (DOMS) Nampo M 2016 15 317 C PBMT had been criticized for not being effective. (Baroni & Leal-Junior, 2016). ( Baroni & Leal-Junior 2016 ).
Chronic backache Chronic backache M 2015 7 211 B / C / PBMT did not reduce or increase the pain
Beard disorder Chen M 2015 14 454 C / PBMT had not reduced the pain but had provided functional improvement
Athletic ability Leal-Junior M 2015 13 134 C PBMT increased the sports ability and accelerated the recovery after the exercise
Arthritis (knees) Huang M 2015 9 518 B PBMT did not reduce the pain. However, there had been a positive outcome shown at a different study (Stausholm et. al, 2016)( Stausholm et al., 2016 ).
Orthodontic treatment Ge M 2015 9 211 C PBMT notably helped with the teeth movement
Lymphedema (breast cancer) Smoot M 2014 7 262 C PBMT reduced the pain and upper limb volume
Neck pain SBU S 2014 18 1007 C PBMT reduced the pain
Mucositis inflammation Oberoi M 2014 18 1144 B PBMT reduced the pain and lessened the risk of worsening inflammation
Sports performance Borsa S 2013 10 147 B PBMT increased the sports performance and accelerated the recovery after the exercise
Chronic neck pain Gross M 2013 2 109 C PBMT improved the following markers (pain, disability, QoL, and GPE).
Tooth extraction Brignard. S/td> 2012 9 599 C PBMT did not do any change
Tendinopathies Tumilty M 2010 25 963 B / Out of all the studies, 12 studies indicated that PBMT was effective while 13 studies suggested that PBMT showed no change
Neck pain Chow M 2009 16 820 B PBMT reduced the pain
Tennis elbow Bjordal M 2008 13 730 B / C PBMT reduced the pain
Acute pain Bjordal S 2006 9 609 B / C PBMT reduced the pain
Neck pain Chow S 2005 5 273 C PBMT reduced the pain
Chronic joint disorder Bjordal S 2003 11 565 C PBMT reduced the pain
M = 메타 분석; S = 체계적인 검토; N = 인원 수; n = 과목 수
Above clinical result chart includes the analysis on the quality of such results. B indicates normal effectiveness,
C indicates weak effectiveness. Such analysis had been evidenced based on the standards used by UK Cochrane Library ( https://www.cochrane.org/ ) .
From 2014 to 2018, a lot of these systematically reviewed trials have been published.
Currently, PBM research is ever increasing at a rapid speed and there are over 400 related studies published worldwide. We project that by 2020,
there would be more than thousand related published studies available.
To conclude, PBMT is beneficial for various different diseases.
Click to view more related studies

PBMT at cellular, mitochondrial level

  • Increase in oxygen
    consumption
  • Increase in the mitochondrial membrane
  • Increase in ATP
    and cAMP
  • Release of Nitric Oxide (NO)
  • Short occurrence of ROS
  • Molecular change to the calcium

Signaling through stimulating the mitochondria

  • Generation of the growth factor
  • extracellular matrix deposition
  • Increase in the cellular multiplication and activity
  • Anti-apoptosis suppression

查看病毒相关论文

关于PBMT对病毒的治疗和预防以及后遗症的临床研究一直不断进行中。  点击按钮可查看韩国国立卫生院：可阅览医学图书馆研究资料。
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Disclaimer: This content consists of medical papers and academic information and is not intended to diagnose, treat diseases, or replace a doctor's advice, and all outcomes may vary from person to person.
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